HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,2-Ethanediamine, N1,N1-bis(1-methylethyl)- → N-[2-[bis(1-Methylethyl)amino]ethyl]-3-(phenylsulfonyl)-1-piperidinecarboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,2-Ethanediamine, N1,N1-bis(1-methylethyl)- | HCID 8459 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 3-(Phenylsulfonyl)piperidine | HCID 13607983 | — |
| Product | N-[2-[bis(1-Methylethyl)amino]ethyl]-3-(phenylsulfonyl)-1-piperidinecarboxamide | HCID 13608029 | 59.8% |
Reaction Steps
Following the procedure of Example 16, diisopropylaminoethylamine and 1,1'-carbonyldiimidazole and 3-(phenylsulfonyl)piperidine were reacted to give the title compound which was crystallized from diethyl ether-hexane as white solid in 59.8% yield, m.p. 82.5°-84° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04593102 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-90509a2c407944e5b8b6920bf2310138 |
| Source note | uspto-grants-1986_06 |