HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1981835Generated: November 1, 2026
Acetic acid, 2-oxo-, methyl ester → HCID 13309444, compound
https://huagongshe.com/reaction/1981835
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic acid, 2-oxo-, methyl ester | HCID 70205 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | methylphosphonoylmethane | HCID 178503022 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 13309444 | HCID 13309444 | — |
Reaction Steps
A solution of 17.6 g (0.2 mol) of methyl glyoxylate in 30 ml of dioxane is added dropwise to a solution of 15.6 g (0.2 mol) of dimethylphosphine oxide in 50 ml of dioxane. A spatula-tip of sodium methylate is added, the mixture is stirred at 25° C. for 24 hours and the evaporated residue is freed from adhering dioxane under a high vacuum and taken up in ethyl acetate to give, after trituration, 16.4 g (49.4%) of colorless product of melting point 84°-86°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04594098 |
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| Source dataset | uspto-grants-1986_06 |
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| ORD ID | ord-b704957188f2486885126773886bd96a |
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| Source note | uspto-grants-1986_06 |
|---|
