HCID 14598772, compound → HCID 18360905, compound

HRID 1981957Notes

Reaction equation

HRID 1981957 reaction equation
[N+:1]([C:4]1([N+:10]([O-:12])=[O:11])[CH2:9][O:8]C(=O)[CH2:5]1)([O-:3])=[O:2].[N+](C(C)C(O)=O)([O-])=[O:14]>>[N+:1]([C:4]([N+:10]([O-:12])=[O:11])([CH3:5])[C:9]([OH:14])=[O:8])([O-:3])=[O:2]

Participants

3

Reactant 2

HCID 14598772HCID 14598772, compoundHCID 14692681HCID 14692681, compound

Product 1

HCID 18360905HCID 18360905, compound

Procedure

A unique synthesis involving the latter substrates covers the synthesis of 3,3-dinitrobutyrolactone. 2-nitropropionic acid can be nitrated to provide 2,2-dinitropropionic acid, which is formylated to give the corresponding methylol derivative, which is then cyclized to the lactone.

Workup

  1. customA unique synthesis

Sources & evidence

ORD record
ord-17f86ade9544497f8983fcd88557d6ca
Source dataset
uspto-grants-1986_06
Patent number
US04594430

Reaction notes

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