3066-64-6 → Diethyl hexane-1,6-diylbis(hydrogen carbonimidate)
Reaction equation
[CH:1]1([O:7][C:8]([NH:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][NH:17][C:18]([O:20][CH:21]2CCCC[CH2:22]2)=[O:19])=[O:9])CCCC[CH2:2]1>C(O)C>[CH2:21]([O:20][C:18]([NH:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][NH:10][C:8]([O:7][CH2:1][CH3:2])=[O:9])=[O:19])[CH3:22]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 230 °C
Procedure
368 g of 1,6-bis-(cyclohexoxycarbonylamino)-hexane (1 mol) were dissolved in 1.5 l ethanol and heated for two hours at 230° C. in a 3 l autoclave. After cooling, the reaction mixture was separated from the excess ethanol and resultant cyclohexanol in a water jet vacuum. The reaction product was examined by high pressure liquid chromatography (HPLC). A yield of 240 g of 1,6-bis-(ethoxycarbonylamino)-hexane was produced corresponding to a yield of 92% of the theoretical yield.
Workup
- temperatureAfter cooling
- customthe reaction mixture was separated from the excess ethanol and resultant cyclohexanol in a water jet vacuum
Sources & evidence
- ORD record
- ord-1e20cdca7f004256b25ea78259db81d7
- Source dataset
- uspto-grants-1986_06
- Patent number
- US04594441
Reaction notes
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