HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → HCID 53710614, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | 3,3,3-Trifluoropropene | HCID 12672 | — |
| Reactant | 2-Chloro-1-iodo-4-nitrobenzene | HCID 96640 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Catalyst | palladium(II) acetate | HCID 167845 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 53710614 | HCID 53710614 | — |
Reaction Steps
2.85 g of 3-chloro-4-iodo-nitro-benzene, 0.95 g of sodium acetate, 0.0048 g of Pd(OAc)2, 0.048 g of triphenylphosphine and 2 g of 3,3,3-trifluoro-propene were reacted in 25 ml of dimethylformamide at 130° C. for 24 h, under stirring. The reaction mixture was cooled, breathered to atmospheric pressure, poured in water and extracted with ethyl ether (5×80 ml). The organic extract was anhydrified on Na2SO4 and purified by chromatography on silica gel column (hexane 95%--ethyl-acetate 5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04594451 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-546e4249651e4bd09c2fde8c288d0f08 |
| Source note | uspto-grants-1986_06 |