HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 56980812, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Phenoxyacetyl chloride | HCID 69703 | — |
| Reactant | HCID 57011224 | HCID 57011224 | — |
| Solvent | Oxolane--water (1/1) | HCID 21881883 | — |
| Product | HCID 56980812 | HCID 56980812 | — |
Reaction Steps
For example, N-(diphenylmethoxycarbonylmethyl)-3-amino- 2-azetidinone is reacted in THF-water with phenoxyacetyl chloride in the presence of triethylamine to provide N-(diphenylmethoxycarbonylmethyl)-3-phenoxyacetamido-2-azetidinone. Treatment of the product with trifluoroacetic acid in the presence of anisole removes the diphenylmethyl ester group to provide the N-(carboxymethyl)azetidinone.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04595532 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-9aa7a89809fb462287407d8552ba46f9 |
| Source note | uspto-grants-1986_06 |