Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 1-Methylazulene | HCID 136611 | — |
| Product | HCID 23690675 | HCID 23690675 | — |
Reaction Steps
Acetic anhydride in an amount of 10 ml is added to 1.0 g. of 1-methylazulene under cooling with ice-water, sulfuric acid in an amount of 3.4 g. is added dropwise and the reaction mixture is stirred for 4 hours at 0° C. Then, the reaction mixture is alkalized to pH8-9 by adding 40% of sodium hydroxide solution and the generated solid is collected and dried. The product is recrystalized from 95% ethanol to give 1.1 g. of the objective compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04595694 |
|---|
| Source dataset | uspto-grants-1986_06 |
|---|
| ORD ID | ord-1d1769a5861f45b4ac2a6aa93ad0e752 |
|---|
| Source note | uspto-grants-1986_06 |
|---|
