HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 5-Chloro-2-methoxybenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-Chloro-salicylaldehyde | HCID 12481 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 5-Chloro-2-methoxybenzaldehyde | HCID 3718356 | 98.2% |
Reaction Steps
4.3 g of 5-chlorosalicylaldehyde, together with 7.8 g of methyl iodide and 5.7 g of potassium carbonate, in 100 ml of acetone are heated to reflux (1 hour). After filtration, the filtrate is concentrated. 4.6 g of the title compound are obtained as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04595685 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-6802af6ee8664fb38b35b713129f70e4 |
| Source note | uspto-grants-1986_06 |