HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 13489983, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1(3H)-Isobenzofuranone, 3-bromo- | HCID 96218 | — |
| Reactant | N-(4-Bromophenyl)-4-[(dimethylsulfamoyl)amino]benzamide | HCID 13321993 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 13489983 | HCID 13489983 | 51.1% |
Reaction Steps
To a solution of 1.0 g of 4'-bromo-4-[(dimethylaminosulfonyl)amino]benzanilide 10 and 10 ml of dried acetone are added 416 mg of potassium carbonate powder and 642 mg of 3-bromophthalide 11, and the mixture is refluxed for 1 hour. The reaction mixture is concentrated; to the residue is added water, and the precipitating crystals are collected by filtration and recrystallized from acetonitrile to give 680 mg of 4'-bromo-4-[(dimethylaminosulfonyl)(3-phthalidyl)amino]benzanilide 12 as crystals, m.p. 244°-245.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04595780 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-77e0831413064f8585a44a85004a737a |
| Source note | uspto-grants-1986_06 |