反应详情

390 mg of Z-Sar-His-Lys(Boc)-OMe are dissolved in 10 ml of 95% strength MeOH and, after the addition of 40 mg of Pd-on-carbon, hydrogenated with CO2 -absorption until saturation. The catalyst is filtered off, the filtrate is concentrated to dryness and the amorphous residue is dried to constant weight in a high vacuum at 40°, yielding H-Sar-His-Lys(Boc)-OMe; Rf (G)=0.1; Rf (E)=0.25.

1. filtrationThe catalyst is filtered off
2. concentrationthe filtrate is concentrated to dryness
3. customthe amorphous residue is dried to constant weight in a high vacuum at 40°