HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azobisisobutyronitrile → 5-(Bromomethyl)-4-(4-chlorophenyl)-2-ethyl-1,3-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azobisisobutyronitrile | HCID 6547 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | 4-(4-Chlorophenyl)-2-ethyl-5-methyl-1,3-oxazole | HCID 23316581 | — |
| Solvent | Carbon Tetrachloride | HCID 5943 | — |
| Product | 5-(Bromomethyl)-4-(4-chlorophenyl)-2-ethyl-1,3-oxazole | HCID 23316585 | 100% |
Reaction Steps
2-Ethyl-4-(4-chlorophenyl)-5-methyloxazole (6.6 g) was brominated with N-bromosuccinimide (5.4 g) in carbon tetrachloride (90 ml) in the presence of azobisisobutyronitrile (0.3 g) in the same manner as Example 5-(2). The procedure gave an oil of 5-bromomethyl-4-(4-chlorophenyl)-2-ethyloxazole, yield 100%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04596816 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-d3e3cc90eed64dd296ea75bb110a879d |
| Source note | uspto-grants-1986_06 |