HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium → HCID 23316502, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | HCID 13041786 | HCID 13041786 | — |
| Reactant | Monosodium phosphate | HCID 23672064 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 23316502 | HCID 23316502 | 94.7% |
Reaction Steps
30 mg of sodium is dissolved in 15 ml of absolute methanol. Then, 300 mg of 4-methoxymethyl-beta-carboline-3-carboxylic-acid-ethylester is added and the mixture is heated with reflux for 2 h. The cooled solution is poured into a sodium dihydrogen phosphate solution and extracted with ethyl acetate. Crystallization in hexane/methylene-chloride yields 270 mg of 4-methoxymethyl-beta-carboline-3-carboxylic-acid-methylester with a m.p. 134°-135° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04596808 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-2abef2d825b64ae6bfdefe2064c04cfd |
| Source note | uspto-grants-1986_06 |