HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → HCID 131713411, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Triethyl phosphite | HCID 31215 | — |
| Reactant | HCID 13136250 | HCID 13136250 | — |
| Product | HCID 131713411 | HCID 131713411 | — |
Reaction Steps
460 mg of 6-(3-chloro-1-propinyl)-beta-carboline-3-carboxylic-acid-ethylester is stirred in 4 ml of triethylphosphite for 3 h at 120°-130° C. The mixture, after being cooled, is thoroughly stirred with ether and the ether-soluble part is chromatographed after evaporation on 50 g of silica gel using methylene-chloride/ethanol (10/2). 105 mg of 6-[3-diethoxyphosphoryl-1-propinyl]-beta-carboline-3-carboxylic-acid-ethylester is obtained in the form of an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04596808 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-84f9b9d95ce04905a875efd82d13a74e |
| Source note | uspto-grants-1986_06 |