反应详情

Combine 9 g (46 mmol) of the product from Example 3 with 50 g of "activated" manganese dioxide in 200 ml of methylene chloride, and heat to reflux for 8 hr. Filter off the solids and remove the solvent in vacuo. Crystallize the residue from ether to provide the title compound.

1. temperatureto reflux for 8 hr
2. filtrationFilter off the solids
3. customremove the solvent in vacuo
4. customCrystallize the residue from ether