Formaldehyde → N-(5-Bromo-pyridin-2-yl)-3-(7-isopropyl-pyrido[2,3-d]pyrimidin-4-ylamino)-4-[4-(methyl-propyl-amino)-phenylsulfanyl]-benzamide
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([c:10]2[cH:11][c:12]([NH:27][c:28]3[c:29]4[c:30]([n:31][cH:32][n:33]3)[n:34][c:35]([CH:38]([CH3:39])[CH3:40])[cH:36][cH:37]4)[c:13]([S:16][c:17]3[cH:18][cH:19][c:20]([NH:23][CH2:24][CH2:25][CH3:26])[cH:21][cH:22]3)[cH:14][cH:15]2)=[O:41])[n:6][cH:7]1.[C:42]([O:43][BH-:44]([O:45][C:46](=[O:47])[CH3:48])[O:49][C:50](=[O:51])[CH3:52])(=[O:53])[CH3:54].[CH2:56]=[O:57].[CH3:58][OH:59].[Cl:60][CH2:61][Cl:62].[Na+:55]>>[Br:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([c:10]2[cH:11][c:12]([NH:27][c:28]3[c:29]4[c:30]([n:31][cH:32][n:33]3)[n:34][c:35]([CH:38]([CH3:39])[CH3:40])[cH:36][cH:37]4)[c:13]([S:16][c:17]3[cH:18][cH:19][c:20]([N:23]([CH2:24][CH2:25][CH3:26])[CH3:42])[cH:21][cH:22]3)[cH:14][cH:15]2)=[O:41])[n:6][cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d00c7321c33e40bb8b472db043a7d75a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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