HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2-(6-Aminopyridin-2-yl)-2-methoxyiminoacetic acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-(6-Formamidopyridin-2-yl)-2-methoxyiminoacetic acid | HCID 54326251 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-(6-Aminopyridin-2-yl)-2-methoxyiminoacetic acid hydrochloride | HCID 86737725 | 104.7% |
Reaction Steps
A suspension of 2-(6-formamidopyridin-2-yl)-2-methoxyiminoacetic acid (1.5 g.) and conc. hydrochloric acid (0.77 g.) in methanol (30 ml.) was stirred at room temperature for 45 minutes. After concentrating the resultant solution under reduced pressure, the residue was washed with diethyl ether. The precipitates were collected by filtration to give 2-(6-aminopyridin-2-yl)-2-methoxyiminoacetic acid hydrochloride (1.63 g.), mp 100° to 105° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04596869 |
| Source dataset | uspto-grants-1986_06 |
| ORD ID | ord-4e89a046ecac483a84cfe3b542c41f84 |
| Source note | uspto-grants-1986_06 |