Sodium Methoxide → HCID 9822503, compound

Participants

Reaction Steps

Sodium methoxide (28% methanol solution; 0.3 mL) was added to a solution of 5-acetoxymethyl-2-(4-ethylbenzyl)phenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside (1.0 g) in methanol (12 mL), and the mixture was stirred at room temperature for 40 minutes. The solvent was removed under reduced pressure. The residue was purified by column chromatography on silica gel (eluent: dichloromethane/methanol=7/1) to give 2-(4-ethylbenzyl)-5-hydroxymethylphenyl β-D-glucopyranoside (0.68 g).

Provenance & Evidence