HCID 21909294, compound → HCID 21909297, compound

Participants

Reaction Steps

To a solution of 2-[3-benzyloxy-4-(4-ethylbenzyl)-phenyl]acetoamide (0.38 g) in methanol (5 mL) was added 10% palladium-carbon powder (0.075 g), and the mixture was stirred under a hydrogen atmosphere at room temperature for 4 hours. Insoluble materials were removed by filtration, and the solvent of the filtrate was removed under reduced pressure. The residue was purified by column chromatography on silica gel (eluent: dichloromethane/methanol=30/1-20/1) to give 2-[4-(4-ethylbenzyl)-3-hydroxyphenyl]acetoamide (0.16 g).

Provenance & Evidence