HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Dichlorobenzaldehyde → HCID 68802809, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Dichlorobenzaldehyde | HCID 13404 | — |
| Reactant | 1-(4-Bromophenyl)propan-2-one | HCID 736332 | — |
| Catalyst | Piperidine | HCID 8082 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 68802809 | HCID 68802809 | 98.2% |
Reaction Steps
A mixture of 15.9 g of 1-(4-bromophenyl)acetone, 13 g of 2,4-dichlorobenzaldehyde and 0.5 g of piperidine in 300 ml of benzene is heated under reflux for 18 hours, removing the water that forms by means of a Dean Stark. 0.3 g of piperidine is added, and it is refluxed for a further 24 hours. The reaction mixture is concentrated under vacuum, obtaining 27 g of the expected compound in the form of oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07541361B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-26440c41d688488b8bf6a244deb56f0f |
| Source note | uspto-grants-2009_06 |