HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 4-chloro-1-(chloromethyl)-1H-pyrazole hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | (4-chloro-1H-pyrazol-1-yl)methanol | HCID 7017837 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 4-chloro-1-(chloromethyl)-1H-pyrazole hydrochloride | HCID 23149119 | — |
Reaction Steps
2.73 g of 4-chloro-1H-pyrazole-1-ylmethanol was dissolved to 20 ml of dichloromethane. 4.4 ml of thionyl chloride was added to the solution, followed by stirring at room temperature for overnight. The reaction mixture was concentrated under reduced pressure to obtain 2.90 g of 4-chloro-1-(chloromethyl)-1H-pyrazole hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07541374B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-4ba79de6830f453fbdf6b7841f6f2834 |
| Source note | uspto-grants-2009_06 |