Thionyl Chloride → HCID 23149175, compound

HRID 1983035Notes

Reaction equation

HRID 1983035 reaction equation
[Br:1][C:2]1[N:6]([CH2:7]O)[N:5]=[C:4]([C:9]([CH3:12])([CH3:11])[CH3:10])[N:3]=1.S(Cl)([Cl:15])=O>ClCCl>[ClH:15].[Br:1][C:2]1[N:6]([CH2:7][Cl:15])[N:5]=[C:4]([C:9]([CH3:12])([CH3:11])[CH3:10])[N:3]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 23149129HCID 23149129, compound

Product 1

HCID 23149175HCID 23149175, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

2.88 g of 5-bromo-3-t-butyl-1H-1,2,4-triazole 1-ylmethanol was dissolved to 100 ml of dichloromethane. 4.2 ml of thionyl chloride was added to the solution, followed by stirring at room temperature for 3 hours. The reaction mixture was concentrated under reduced pressure. Chloroform was added to the residue and filtered. The filtrate was concentrated under reduced pressure to obtain 2.03 g of 5-bromo-3-t-butyl-1-(chloromethyl)-1H-1,2,4-triazole hydrochloride.

Workup

  1. concentrationThe reaction mixture was concentrated under reduced pressure
  2. additionChloroform was added to the residue
  3. filtrationfiltered
  4. concentrationThe filtrate was concentrated under reduced pressure

Sources & evidence

ORD record
ord-1cc0a4d89b454c058e9b05e6eb05d707
Source dataset
uspto-grants-2009_06
Patent number
US07541374B2

Reaction notes

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