Thionyl Chloride → HCID 23149134, compound

HRID 1983041Notes

Reaction equation

HRID 1983041 reaction equation
[F:1][C:2]([F:14])([C:7]1[N:11]=[CH:10][N:9]([CH2:12]O)[N:8]=1)[C:3]([F:6])([F:5])[F:4].S(Cl)([Cl:17])=O>ClCCl>[Cl:17][CH2:12][N:9]1[CH:10]=[N:11][C:7]([C:2]([F:14])([F:1])[C:3]([F:6])([F:5])[F:4])=[N:8]1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 231491283-(pentafluoroethyl)-1H-1,2,4-triazole 1-ylmethanol

Product 1

HCID 23149134HCID 23149134, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

1.52 g of 3-(pentafluoroethyl)-1H-1,2,4-triazole 1-ylmethanol was dissolved to 50 ml of dichloromethane, and 2.7 ml of thionyl chloride was added to the solution, followed by stirring at room temperature for overnight. The reaction mixture was concentrated under reduced pressure to obtain 1.36 g of 1-(chloromethyl)-3-(pentafluoroethyl)-1H-1,2,4-triazole.

Workup

  1. additionwas added to the solution
  2. concentrationThe reaction mixture was concentrated under reduced pressure

Sources & evidence

ORD record
ord-f551d250f7b5451899a0a35fc0cf192b
Source dataset
uspto-grants-2009_06
Patent number
US07541374B2

Reaction notes

Loading…