Formaldehyde → 4-bromo-3-(pentafluoroethyl)-1H-pyrazole-1-ylmethanol

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

The mixture of 13.72 g of 4-bromo-3-(pentafluoroethyl)-1H-pyrazole and 3.00 g of paraformaldehyde was stirred at 130° C. for 5 hours. After the reaction mixture was cooled to room temperature, acetone was added. The mixture was filtered. The filtrate was concentrated under reduced pressure. Hexane was added to the filtrate, as a result, a crystal was formed. The crystal was collected to obtain 7.69 g of 4-bromo-3-(pentafluoroethyl)-1H-pyrazole-1-ylmethanol.

Herkunft & Nachweise