4-Nitrobenzoic Acid → HCID 16722698, compound

HRID 1983112Notes

Reaction equation

HRID 1983112 reaction equation
[CH3:1][C:2]1[O:6][N:5]=[C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:3]=1[C:13]([NH:15][NH2:16])=[O:14].[N+:17]([C:20]1[CH:28]=[CH:27][C:23]([C:24](O)=O)=[CH:22][CH:21]=1)([O-:19])=[O:18]>>[CH3:1][C:2]1[O:6][N:5]=[C:4]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:3]=1[C:13]1[O:14][C:24]([C:23]2[CH:27]=[CH:28][C:20]([N+:17]([O-:19])=[O:18])=[CH:21][CH:22]=2)=[N:16][N:15]=1

Participants

3

Reactant 2

HCID 61084-Nitrobenzoic AcidHCID 7279245-Methyl-3-phenyl-4-isoxazolecarbohydrazide

Product 1

HCID 16722698HCID 16722698, compoundYield 50%

Procedure

As described for example 2, 5-methyl-3-phenyl-isoxazole-4-carboxylic acid hydrazide (2.00 g, 9.21 mmol) was converted using 4-nitro-benzoic acid instead of o-toluic acid to the title compound (1.59 mg, 50%) which was obtained as an off-white solid. MS: m/e=349.3 [M+H]+.

Sources & evidence

ORD record
ord-ad5db4fec049415f8e325d9456596f96
Source dataset
uspto-grants-2009_06
Patent number
US07541372B2

Reaction notes

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