HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indole-5-Carboxylic Acid → HCID 67215437, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indole-5-Carboxylic Acid | HCID 74280 | — |
| Reactant | 5-Methyl-3-phenyl-4-isoxazolecarbohydrazide | HCID 727924 | — |
| Product | HCID 67215437 | HCID 67215437 | 55% |
Reaction Steps
As described for example 2, 5-methyl-3-phenyl-isoxazole-4-carboxylic acid hydrazide (500 mg, 2.30 mmol) was converted using indole-5-carboxylic acid instead of o-toluic acid to the title compound (SiO2, heptane:ethyl acetate:dichloromethane=70:10:20 to 40:40:20, 430 mg, 55%) which was obtained as a colorless liquid. MS: m/e=343.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07541372B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-3364014149e64057b630e92fd10956f3 |
| Source note | uspto-grants-2009_06 |