HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Difluorobenzoic acid → HCID 16723005, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Difluorobenzoic acid | HCID 370590 | — |
| Reactant | 5-Methyl-3-phenyl-4-isoxazolecarbohydrazide | HCID 727924 | — |
| Product | HCID 16723005 | HCID 16723005 | 35% |
Reaction Steps
As described for example 2, 5-methyl-3-phenyl-isoxazole-4-carboxylic acid hydrazide (200 mg, 0.92 mmol) was converted using 2,3-difluorobenzoic acid instead of o-toluic acid to the title compound (SiO2, heptane:ethyl acetate:dichloromethane=70:10:20 to 40:40:20, 108 mg, 35%) which was obtained as a white solid. MS: m/e=340.2 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07541372B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-013c39f7155642868aa22eb83922446f |
| Source note | uspto-grants-2009_06 |