HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethylamine → HCID 67215420, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethylamine | HCID 8018 | — |
| Reactant | 2-(4-Fluoro-2-methoxy-phenyl)-5-(5-methyl-3-phenyl-isoxazol-4-yl)-[1,3,4]oxadiazole | HCID 16722645 | — |
| Product | HCID 67215420 | HCID 67215420 | 34% |
Reaction Steps
As described for example 26, 2-(4-fluoro-2-methoxy-phenyl)-5-(5-methyl-3-phenyl-isoxazol-4-yl)-[1,3,4]oxadiazole (200 mg, 0.57 mmol) was converted using 2-methoxyethylamine instead of thiomorpholine to the title compound (SiO2, heptane:ethyl acetate=50:50 to 0:100, 78 mg, 34%) which was obtained as an off-white foam. MS: m/e=407.4 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07541372B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-9da326e8aaac4edfafb148d574696ef8 |
| Source note | uspto-grants-2009_06 |