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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1983316Generated: November 1, 2026

Ethyl Acetate → [3-Cyclopentanecarbonyl-4-(3-[1,3,4]thiadiazol-2-yl-ureido)-phenyl]-acetic acid ethyl ester

https://huagongshe.com/reaction/1983316

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetateHCID 8857—
Reactant1,3,4-Thiadiazol-2-amineHCID 19909—
Reactant(4-Amino-3-cyclopentanecarbonylphenyl)acetic acid ethyl esterHCID 66998892—
Product[3-Cyclopentanecarbonyl-4-(3-[1,3,4]thiadiazol-2-yl-ureido)-phenyl]-acetic acid ethyl esterHCID 59732786—

Reaction Steps

3-Cyclopentanecarbonyl-4-(3-[1,3,4]thiadiazol-2-yl-ureido)-phenyl]-acetic acid ethyl ester (147 mg, 73%) was prepared from (4-amino-3-cyclopentanecarbonyl-phenyl)-acetic acid ethyl ester (138 mg, 0.5 mmol) and [1,3,4]thiadiazol-2-ylamine (60 mg, 0.6 mmol) following the general procedure D.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07541373B2
Source datasetuspto-grants-2009_06
ORD IDord-897598d10a8e4013b503e87d2d6d3867
Source noteuspto-grants-2009_06