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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1983377Generated: October 31, 2026

Methylamine → HCID 59732693, compound

https://huagongshe.com/reaction/1983377

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
ReactantTetrahydrofuranHCID 8028—
ReactantHCID 59732813HCID 59732813—
ProductHCID 59732693HCID 5973269365%

Reaction Steps

2-(2-{3-[5-Fluoro-2-(2-methoxy-benzoyl)-phenyl]-ureido}-thiazol-4-yl)-N-methyl-acetamide (144 mg, 65%) was prepared from (2-{3-[5-fluoro-2-(2-methoxy-benzoyl)-phenyl]-ureido}-thiazol-4-yl)-acetic acid (215 mg, 0.5 mmol) and 1N solution of methyl amine in THF (0.5 mL, 0.5 mmol) following the general procedure K.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07541373B2
Source datasetuspto-grants-2009_06
ORD IDord-69d838e314264c7e9cb8d48bb2b0ad83
Source noteuspto-grants-2009_06