Dichloromethane → [1-(4-Fluoro-phenylcarbamoyl)-4-(4-isopropyl-phenylcarbamoyl)-piperidin-4-yl]-carbamic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([C:14]([NH:15][c:16]2[cH:17][cH:18][c:19]([CH:22]([CH3:23])[CH3:24])[cH:20][cH:21]2)=[O:25])[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1)=[O:26].[Cl:37][CH2:38][Cl:39].[F:27][c:28]1[cH:29][cH:30][c:31]([N:34]=[C:35]=[O:36])[cH:32][cH:33]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][C:8]1([C:14]([NH:15][c:16]2[cH:17][cH:18][c:19]([CH:22]([CH3:23])[CH3:24])[cH:20][cH:21]2)=[O:25])[CH2:9][CH2:10][N:11]([C:35]([NH:34][c:31]2[cH:30][cH:29][c:28]([F:27])[cH:33][cH:32]2)=[O:36])[CH2:12][CH2:13]1)=[O:26]Participants
4
Sources & evidence
- ORD record
- ord-c997c21ccb934187b36495c00540fb23
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…