huagongshe.com
HRID1983602

反应详情

EQUATION

反应方程式

HRID 1983602 的结构方程式

REACTANTS

反应物

4
结构：COC(=O)c1ccc(Br)cc1
HCID12081

Benzoic acid, 4-bromo-, methyl ester

C8H7BrO2

结构：[Li]N([Si](C)(C)C)[Si](C)(C)C
HCID178418261

未命名化合物

结构：CC1SC(N[C@@H](C)c2ccc(F)cc2)=NC1=O
HCID178435111

未命名化合物

结构：C[C@H](NC1=NC(=O)C(C)(c2ccc(C#N)cc2)S1)c1ccccc1C(F)(F)F
HCID178461986

未命名化合物

PRODUCTS

生成物

1
结构：COC(=O)c1ccc(C2(C)SC(N[C@@H](C)c3ccc(F)cc3)=NC2=O)cc1
HCID178497560

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from the reaction of 5-methyl-2-((S)-1-(4-fluorophenyl)ethylamino)thiazol-4(5H)-one with methyl-4-bromobenzoate using the procedure described for 2a. 2.0 equivalent of NaN(SiMe3)2 or LiN(SiMe3)2 with reaction temperature of 50° C. was used. MS (ESI, pos. ion) m/z: 387 (M+1).