6-(aminomethyl)benzo[c][1,2]oxaborol-1(3H)-ol → 8-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)methyl)indolizine-5-carboxamide

HRID 198367Notes

Reaction equation

HRID 198367 reaction equation
[Cl:1][c:2]1[cH:3][c:4]([C:9]2([C:26]([F:27])([F:28])[F:29])[CH2:10][C:11]([c:14]3[cH:15][cH:16][c:17]([C:23](=[O:24])[OH:25])[n:18]4[cH:19][cH:20][cH:21][c:22]34)=[N:12][O:13]2)[cH:5][c:6]([Cl:8])[cH:7]1.[NH2:30][CH2:31][c:32]1[cH:33][cH:34][c:35]2[c:36]([cH:41]1)[B:37]([OH:40])[O:38][CH2:39]2>>[Cl:1][c:2]1[cH:3][c:4]([C:9]2([C:26]([F:27])([F:28])[F:29])[CH2:10][C:11]([c:14]3[cH:15][cH:16][c:17]([C:23](=[O:25])[NH:30][CH2:31][c:32]4[cH:33][cH:34][c:35]5[c:36]([cH:41]4)[B:37]([OH:40])[O:38][CH2:39]5)[n:18]4[cH:19][cH:20][cH:21][c:22]34)=[N:12][O:13]2)[cH:5][c:6]([Cl:8])[cH:7]1

Participants

3

Reactant 2

HCID 682815336-(aminomethyl)benzo[c][1,2]oxaborol-1(3H)-olHCID 866855228-[5-(Trifluoromethyl)-5-(3,5-dichlorophenyl)-2-isoxazoline-3-yl]indolizine-5-carboxylic acid

Product 1

HCID 715765788-(5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-((1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)methyl)indolizine-5-carboxamide

Sources & evidence

ORD record
ord-b4a36c6ae0f148a09bd4d8a5c8d84434
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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