HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl 4-(4-chlorophenyl)-4-cyanopiperidine-1-carboxylate → 2-[4-(4-Chloro-phenyl)-piperidin-4-yl]-propan-2-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl 4-(4-chlorophenyl)-4-cyanopiperidine-1-carboxylate | HCID 49760270 | — |
| Reactant | 4-(4-Chloro-phenyl)-4-(1-hydroxy-1-methyl-ethyl)-piperidine-1-carboxylic acid tert-butyl ester | HCID 66758512 | — |
| Product | 2-[4-(4-Chloro-phenyl)-piperidin-4-yl]-propan-2-ol | HCID 23136885 | — |
Reaction Steps
The title compound was prepared by following the procedure of Example 456, step 3, but replacing 4-(4-chloro-phenyl)-4-cyano-piperidine-1-carboxylic acid tert-butyl ester with: 4-(4-chloro-phenyl)-4-(1-hydroxy-1-methyl-ethyl)-piperidine-1-carboxylic acid tert-butyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07541365B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-37d3af6359984ad9b91f2df39071ac77 |
| Source note | uspto-grants-2009_06 |