Methanol → 3-methoxy-N-(5-methyl-2-pyridinyl)-2-(1-phenylpyrazolo[5,4-d]pyrimidin-4-yl)oxypropanamide

HRID 198380Notes

Reaction equation

HRID 198380 reaction equation
[CH3:32][OH:33].[Cl:1][c:2]1[c:3](-[n:8]2[n:9][cH:10][c:11]3[c:12]2[n:13][cH:14][n:15][c:16]3[O:17][CH:18]([C:19](=[O:20])[NH:21][c:22]2[n:23][cH:24][c:25]([CH3:28])[cH:26][cH:27]2)[CH2:29][O:30][CH3:31])[cH:4][cH:5][cH:6][cH:7]1.[Pd:34]>>[cH:2]1[c:3](-[n:8]2[n:9][cH:10][c:11]3[c:12]2[n:13][cH:14][n:15][c:16]3[O:17][CH:18]([C:19](=[O:20])[NH:21][c:22]2[n:23][cH:24][c:25]([CH3:28])[cH:26][cH:27]2)[CH2:29][O:30][CH3:31])[cH:4][cH:5][cH:6][cH:7]1

Participants

4

Reactant 3

HCID 887MethanolHCID 23938PalladiumHCID 575042462-{[1-(2-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]oxy}-3-methoxy-N-(5-methylpyridin-2-yl)propanamide

Product 1

HCID 668132753-methoxy-N-(5-methyl-2-pyridinyl)-2-(1-phenylpyrazolo[5,4-d]pyrimidin-4-yl)oxypropanamide

Sources & evidence

ORD record
ord-57c594d92c4b4ac08eeb708de8793ae5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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