tert-Butylphosphine → HCID 57713362, compound

Participants

Reaction Steps

3.0 g (17.3 mmol) of 4H-thieno[3,2-b]indole (C′), 4.93 g (17.3 mmol) of 1-bromo-4-octyloxybenzene, and 0.0025 g (1.114×10−2 mmol) of tris(dibenzylideneacetone)dipalladium(0) were dissolved in 1.9 g (19.8 mmol) of t-BuONa, 0.003 g (1.5×102 mmol) of t-butylphosphine, and 50 ml of xylene and the solution was refluxed at 120° C. for 24 hours. Then, the solvent was removed and the resulting product was isolated and purified by column chromatography using toluene/hexane (⅓ by volume) as an eluent, thereby obtaining 5.35 g (yield: 82%) of 4-(4′-octyloxy-phenyl)-4H-thieno[3,2-b]indole (D′).

Provenance & Evidence