5-(piperazin-1-yl)-1H-pyrrolo[2,3-c]pyridine → HCID 16039383, compound

HRID 1984007Notes

Reaction equation

HRID 1984007 reaction equation
[N:1]1([C:7]2[CH:8]=[C:9]3[CH:15]=[CH:14][NH:13][C:10]3=[CH:11][N:12]=2)[CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.Br[CH2:17][CH2:18][C@H:19]1[C:27]2[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=2)[N:21]([C:28]([NH2:30])=[O:29])[CH2:20]1>CS(C)=O>[NH:13]1[C:10]2=[CH:11][N:12]=[C:7]([N:1]3[CH2:2][CH2:3][N:4]([CH2:17][CH2:18][C@H:19]4[C:27]5[C:22](=[CH:23][CH:24]=[CH:25][CH:26]=5)[N:21]([C:28]([NH2:30])=[O:29])[CH2:20]4)[CH2:5][CH2:6]3)[CH:8]=[C:9]2[CH:15]=[CH:14]1

Participants

4

Reactant 2

HCID 468564705-(piperazin-1-yl)-1H-pyrrolo[2,3-c]pyridineHCID 68854031(S)-3-(2-Bromoethyl)-2,3-dihydro-1H-indole-1-carboxylic acid amide

Product 1

HCID 16039383HCID 16039383, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Procedure

from 5-piperazin-1-yl-1H-pyrrolo[2,3-c]pyridine and (S)-3-(2-bromoethyl)-2,3-dihydro-1H-indole-1-carboxylic acid amide. Assignment of the optical rotation was done in dimethyl sulfoxide.

Sources & evidence

ORD record
ord-919f9aac903b441f8375ea9ca672f55f
Source dataset
uspto-grants-2009_06
Patent number
US07544685B2

Reaction notes

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