4-(1,3,4-Oxadiazol-2-yl)phenol → HCID 178456379, compound

HRID 1984021Notes

Reaction equation

HRID 1984021 reaction equation
[CH:1]([N:4]1[CH2:9][CH2:8][N:7]([C:10]([C@H:12]2[CH2:17][CH2:16][C@@H:15]([OH:18])[CH2:14][CH2:13]2)=[O:11])[CH2:6][CH2:5]1)([CH3:3])[CH3:2].[O:19]1[CH:23]=[N:22][N:21]=[C:20]1[C:24]1[CH:29]=[CH:28][C:27](O)=[CH:26][CH:25]=1>>[CH:1]([N:4]1[CH2:9][CH2:8][N:7]([C:10]([C@H:12]2[CH2:13][CH2:14][C@H:15]([O:18][C:27]3[CH:26]=[CH:25][C:24]([C:20]4[O:19][CH:23]=[N:22][N:21]=4)=[CH:29][CH:28]=3)[CH2:16][CH2:17]2)=[O:11])[CH2:6][CH2:5]1)([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 7147704-(1,3,4-Oxadiazol-2-yl)phenolHCID 178456387HCID 178456387, compound

Product 1

HCID 178456379HCID 178456379, compound

Procedure

According to the procedure described for example 1, the title compound had been synthesized from cis-(4-isopropyl-piperazin-1-yl)-(4-hydroxy-cyclohexyl)-methanone and 4-(1,3,4-oxadiazole-2-yl)-phenol. MS (m/e): 399.1 (MH+).

Sources & evidence

ORD record
ord-eb9da7bec7c04b718714da0ca20ed53b
Source dataset
uspto-grants-2009_06
Patent number
US07544683B2

Reaction notes

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