Alpha-Aminobutyric Acid → HCID 68849910, compound

HRID 1984053Notes

Reaction equation

Br[C:2]1[CH:20]=[CH:19][C:5]([C:6]([NH:8][CH:9]2[C:14]([CH3:16])([CH3:15])[C@H:13]3[CH2:17][C@:10]2([CH3:18])[CH2:11][CH2:12]3)=[O:7])=[CH:4][C:3]=1[S:21]([N:24]1[CH2:29][CH2:28][O:27][CH2:26][CH2:25]1)(=[O:23])=[O:22].CCC(N)C(O)=O.[CH3:37][O:38][CH2:39][CH2:40][OH:41]>>[CH3:37][O:38][CH2:39][CH2:40][O:41][C:2]1[CH:20]=[CH:19][C:5]([C:6]([NH:8][CH:9]2[C:14]([CH3:16])([CH3:15])[C@H:13]3[CH2:17][C@:10]2([CH3:18])[CH2:11][CH2:12]3)=[O:7])=[CH:4][C:3]=1[S:21]([N:24]1[CH2:29][CH2:28][O:27][CH2:26][CH2:25]1)(=[O:23])=[O:22]

Participants

Reactant 3

HCID 6657Alpha-Aminobutyric Acid

HCID 80192-Methoxyethanol

HCID 68852883HCID 68852883, compound

Product 1

HCID 68849910HCID 68849910, compound

Procedure

Compound 2L was prepared from 4-bromo-3-(morpholinosulfonyl)-N-((1S,4R)-1,3,3-trimethylbicyclo[2.2.1]heptan-2-yl)benzamide 2.4.AaBa and 2-methoxyethanol 3.3 following the procedure described in Example 2I.

Sources & evidence

ORD record: ord-d63168e533184514bd39483fcdbcd27e
Source dataset: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07544676B2

Reaction notes

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