Tert-Butylamine → (But-3-yn-1-yl)(tert-butyl)amine

Participants

Reaction Steps

A solution of toluene-4-sulfonic acid but-3-ynyl ester (1.57 g, 7.1 mmol) in tert-BuNH2 (3.54 g. 48 mmol) was heated to reflux for 18 h. The reaction mixture was diluted with Et2O (20 mL), filtered, and concentrated to afford the title product. 1H NMR (CDCl3) δ 2.74 (t, 2H), 2.38 (td, 2H), 2.00 (t, 1H), 1.12 (s, 9H).

Provenance & Evidence