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HRID1984088

反应详情

EQUATION

反应方程式

HRID 1984088 的结构方程式

REACTANTS

反应物

2
反应SMILES：COc1c(C)cnc(Cn2cc(I)c3c(Cl)nc(N)nc32)c1C
HCID44228964

4-Chloro-5-iodo-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-2-amine

C15H15ClIN5O

反应SMILES：C#CCCCN1CCN(CC)CC1
HCID86608220

1-Ethyl-4-(4-pentyn-1-yl)piperazine

C11H20N2

PRODUCTS

产物

1
反应SMILES：CCN1CCN(CCCC#Cc2cn(Cc3ncc(C)c(OC)c3C)c3nc(N)nc(Cl)c23)CC1
HCID57713833

未命名化合物

PROCEDURE

实验过程

Sonogashira coupling of 4-chloro-5-iodo-7-((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine with 1-ethyl-4-(pent-4-ynyl)piperazine, according to the general procedure A gave the title compound, as a solid. Mp=142.3-144.1° C. HPLC Rt=4.11 min.