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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984137Generated: October 25, 2026

2-(4-Phenylpiperazin-1-yl)ethan-1-amine → 1-t-Butyl-5-(4-chlorophenyl)-3-[2-(4-phenylpiperazin-1-yl)ethyl]aminomethylpyrazole

https://huagongshe.com/reaction/1984137

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(4-Phenylpiperazin-1-yl)ethan-1-amineHCID 4742503—
Reactant5-(4-Chlorophenyl)-1-t-butylpyrazole-3-carbaldehydeHCID 86611060—
Product1-t-Butyl-5-(4-chlorophenyl)-3-[2-(4-phenylpiperazin-1-yl)ethyl]aminomethylpyrazoleHCID 1603947169.1%

Reaction Steps

Compound 11 was prepared using the same method as that of Example 1 except that 4-phenylpiperazin-1-ylethylamine and 5-(4-chlorophenyl)-1-t-butylpyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-3bf992771850452f94fae902b7966328
Source noteuspto-grants-2009_06