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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984142Generated: November 1, 2026

2-[4-(2,3-Dimethylphenyl)piperazin-1-yl]ethanamine → 1-t-Butyl-5-iso-butyl-3-{2-[4-(2,3-dimethylphenyl)piperazin-1-yl]ethyl}aminomethylpyrazole

https://huagongshe.com/reaction/1984142

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[4-(2,3-Dimethylphenyl)piperazin-1-yl]ethanamineHCID 4521453—
Reactant1-Tert-butyl-5-iso-butyl-3-formylpyrazoleHCID 22493583—
Product1-t-Butyl-5-iso-butyl-3-{2-[4-(2,3-dimethylphenyl)piperazin-1-yl]ethyl}aminomethylpyrazoleHCID 1603953590.8%

Reaction Steps

Compound 17 was prepared using the same method as that of Example 1 except that 4-(2,3-dimethylphenyl)piperazin-1-ylethylamine and 1-t-butyl-5-iso-butylpyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-15f93467af5c4d34bfa862a32105a40c
Source noteuspto-grants-2009_06