HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[4-(2,3-Dimethylphenyl)piperazin-1-yl]ethanamine → 1-t-Butyl-3-{2-[4-(2,3-dimethyl phenyl)piperazin-1-yl]ethyl}aminomethyl-5-(4-chlorophenyl)pyrazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[4-(2,3-Dimethylphenyl)piperazin-1-yl]ethanamine | HCID 4521453 | — |
| Reactant | 5-(4-Chlorophenyl)-1-t-butylpyrazole-3-carbaldehyde | HCID 86611060 | — |
| Product | 1-t-Butyl-3-{2-[4-(2,3-dimethyl phenyl)piperazin-1-yl]ethyl}aminomethyl-5-(4-chlorophenyl)pyrazole | HCID 16038435 | 77.8% |
Reaction Steps
Compound 22 was prepared using the same method as that of Example 1 except that 4-(2,3-dimethylphenyl)piperazin-1-ylethylamine and 5-(4-chlorophenyl)-1-t-butylpyrazole-3-carbaldehyde were used.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07544686B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-fb911c7daa264d72bd60b33354392d35 |
| Source note | uspto-grants-2009_06 |