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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984153Generated: October 25, 2026

4-(2,4-Dimethylphenyl)piperazin-1-ylethylamine → 1-t-Butyl-5-(4-chlorophenyl)-3-{2-[4-(2,4-dimethylphenyl)piperazin-1-yl]-ethyl}aminomethylpyrazole

https://huagongshe.com/reaction/1984153

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2,4-Dimethylphenyl)piperazin-1-ylethylamineHCID 4742466—
Reactant5-(4-Chlorophenyl)-1-t-butylpyrazole-3-carbaldehydeHCID 86611060—
Product1-t-Butyl-5-(4-chlorophenyl)-3-{2-[4-(2,4-dimethylphenyl)piperazin-1-yl]-ethyl}aminomethylpyrazoleHCID 1603856460.3%

Reaction Steps

Compound 33 was prepared using the same method as that of Example 1 except that 4-(2,4-dimethylphenyl)piperazin-1-ylethylamine and 5-(4-chlorophenyl)-1-t-butyl pyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-6b8e05c62e9b4767b62e13b79e870617
Source noteuspto-grants-2009_06