2-[4-(4-Methoxyphenyl)piperazin-1-yl]ethanamine → 3-{2-[4-(4-Methoxyphenyl)piperazin-1-yl]ethyl}aminomethyl-5-propyl-1-phenylpyrazole

HRID 1984158Notes

Reaction equation

HRID 1984158 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][NH2:17])[CH2:11][CH2:10]2)=[CH:5][CH:4]=1.[CH2:18]([C:21]1[N:25]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[N:24]=[C:23]([CH:32]=O)[CH:22]=1)[CH2:19][CH3:20]>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([N:9]2[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][NH:17][CH2:32][C:23]3[CH:22]=[C:21]([CH2:18][CH2:19][CH3:20])[N:25]([C:26]4[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=4)[N:24]=3)[CH2:13][CH2:14]2)=[CH:7][CH:8]=1

Participants

3

Reactant 2

HCID 12561082-[4-(4-Methoxyphenyl)piperazin-1-yl]ethanamineHCID 862610985-Propyl-1-phenylpyrazole-3-carbaldehyde

Product 1

HCID 160386393-{2-[4-(4-Methoxyphenyl)piperazin-1-yl]ethyl}aminomethyl-5-propyl-1-phenylpyrazoleYield 41.3%

Procedure

Compound 39 was prepared using the same method as that of Example 1 except that 4-(4-methoxyphenyl)piperazin-1-ylethylamine and 5-propyl-1-phenylpyrazole-3-carbaldehyde were used.

Sources & evidence

ORD record
ord-c8408e32edeb45f6bf3cd38ccbe54e55
Source dataset
uspto-grants-2009_06
Patent number
US07544686B2

Reaction notes

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