Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984159Generated: October 27, 2026

2-[4-(4-Methoxyphenyl)piperazin-1-yl]ethanamine → 1-t-Butyl-5-iso-butyl-3-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}aminomethylpyrazole

https://huagongshe.com/reaction/1984159

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[4-(4-Methoxyphenyl)piperazin-1-yl]ethanamineHCID 1256108—
Reactant1-Tert-butyl-5-iso-butyl-3-formylpyrazoleHCID 22493583—
Product1-t-Butyl-5-iso-butyl-3-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}aminomethylpyrazoleHCID 1603864035.2%

Reaction Steps

Compound 40 was prepared using the same method as that of Example 1 except that 4-(4-methoxyphenyl)piperazin-1-ylethylamine and 1-t-butyl-5-iso-butylpyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-0f775ef88f654629bbf1c4a23353e066
Source noteuspto-grants-2009_06