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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1984164Generated: October 25, 2026

2-[4-(4-Methoxyphenyl)piperazin-1-yl]ethanamine → 1-t-Butyl-5-(4-chlorophenyl)-3-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}aminomethylpyrazole

https://huagongshe.com/reaction/1984164

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[4-(4-Methoxyphenyl)piperazin-1-yl]ethanamineHCID 1256108—
Reactant5-(4-Chlorophenyl)-1-t-butylpyrazole-3-carbaldehydeHCID 86611060—
Product1-t-Butyl-5-(4-chlorophenyl)-3-{2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl}aminomethylpyrazoleHCID 1603870686%

Reaction Steps

Compound 46 was prepared using the same method as that of Example 1 except that 4-(4-methoxyphenyl)piperazin-1-ylethylamine and 5-(4-chlorophenyl)-1-t-butylpyrazole-3-carbaldehyde were used.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544686B2
Source datasetuspto-grants-2009_06
ORD IDord-48fcb07c21c64f55b804a4b2f5bfa5ed
Source noteuspto-grants-2009_06