HRID1984165

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1256108

2-[4-(4-methoxyphenyl)piperazin-1-yl]ethanamine

C13H21N3O

结构：O=Cc1cc(-c2ccc(C3CCCCC3)cc2)n(-c2ccccc2)n1

HCID86261131

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(N2CCN(CCNCc3cc(-c4ccc(C5CCCCC5)cc4)n(-c4ccccc4)n3)CC2)cc1

HCID16038707

未命名化合物

收率 89.1%

PROCEDURE

实验过程

Compound 47 was prepared using the same method as that of Example 1 except that 4-(4-methoxyphenyl)piperazin-1-ylethylamine and 5-(4-cyclohexylphenyl)-1-phenylpyrazole-3-carbaldehyde were used.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-bf7f7791e2d0491caefa10ebdcf2174c
来源数据集: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07544686B2
来源说明: uspto-grants-2009_06

反应 SMILES

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][CH2:16][NH2:17])[CH2:11][CH2:10]2)=[CH:5][CH:4]=1.[CH:18]1([C:24]2[CH:29]=[CH:28][C:27]([C:30]3[N:34]([C:35]4[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=4)[N:33]=[C:32]([CH:41]=O)[CH:31]=3)=[CH:26][CH:25]=2)[CH2:23][CH2:22][CH2:21][CH2:20][CH2:19]1>>[CH:18]1([C:24]2[CH:29]=[CH:28][C:27]([C:30]3[N:34]([C:35]4[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=4)[N:33]=[C:32]([CH2:41][NH:17][CH2:16][CH2:15][N:12]4[CH2:11][CH2:10][N:9]([C:6]5[CH:5]=[CH:4][C:3]([O:2][CH3:1])=[CH:8][CH:7]=5)[CH2:14][CH2:13]4)[CH:31]=3)=[CH:26][CH:25]=2)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]1