5-Methyl-1-phenylpyrazole-3-carbaldehyde → HCID 16038708, compound

HRID 1984166Notes

Reaction equation

HRID 1984166 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][CH2:17][NH2:18])[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH3:19][C:20]1[N:24]([C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[N:23]=[C:22]([CH:31]=O)[CH:21]=1>>[CH3:19][C:20]1[N:24]([C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)[N:23]=[C:22]([CH2:31][NH:18][CH2:17][CH2:16][N:13]2[CH2:12][CH2:11][N:10]([C:7]3[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=3)[CH2:15][CH2:14]2)[CH:21]=1

Participants

3

Reactant 2

HCID 141352365-Methyl-1-phenylpyrazole-3-carbaldehydeHCID 289138874-(4-Nitrophenyl)piperazin-1-ylethylamine

Product 1

HCID 16038708HCID 16038708, compoundYield 59.6%

Procedure

Compound 49 was prepared using the same method as that of Example 1 except that 4-(4-nitrophenyl)piperazin-1-ylethylamine and 5-methyl-1-phenylpyrazole-3-carbaldehyde were used.

Sources & evidence

ORD record
ord-ddd612d181094a2994d86f410a9227a1
Source dataset
uspto-grants-2009_06
Patent number
US07544686B2

Reaction notes

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