4-(4-Nitrophenyl)piperazin-1-ylethylamine → HCID 16038782, compound

HRID 1984170Notes

Reaction equation

HRID 1984170 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([N:10]2[CH2:15][CH2:14][N:13]([CH2:16][CH2:17][NH2:18])[CH2:12][CH2:11]2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH2:19]([C:23]1[N:27]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[N:26]=[C:25]([CH:34]=O)[CH:24]=1)[CH:20]([CH3:22])[CH3:21]>>[CH2:19]([C:23]1[N:27]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[N:26]=[C:25]([CH2:34][NH:18][CH2:17][CH2:16][N:13]2[CH2:12][CH2:11][N:10]([C:7]3[CH:6]=[CH:5][C:4]([N+:1]([O-:3])=[O:2])=[CH:9][CH:8]=3)[CH2:15][CH2:14]2)[CH:24]=1)[CH:20]([CH3:22])[CH3:21]

Participants

3

Reactant 2

HCID 289138874-(4-Nitrophenyl)piperazin-1-ylethylamineHCID 592816115-Isobutyl-1-phenyl-1H-pyrazole-3-carbaldehyde

Product 1

HCID 16038782HCID 16038782, compoundYield 79.3%

Procedure

Compound 53 was prepared using the same method as that of Example 1 except that 4-(4-nitrophenyl)piperazin-1-ylethylamine and 5-iso-butyl-1-phenylpyrazole-3-carbaldehyde were used.

Sources & evidence

ORD record
ord-9cd15765304740389d03533993c8963e
Source dataset
uspto-grants-2009_06
Patent number
US07544686B2

Reaction notes

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